Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.
Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.
The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).
The Sartobind® S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.