BIOSTAT® A is an entry-level bioreactor | fermenter designed for easy control of cell growth and fermentation. It is therefore ideal for educational purposes.
Higher cell densities
Glass and Single-use
Convenient data storage
Install tubing in three seconds: Open, insert tubing, close – done! No more pinched fingers, torn gloves or tubing slippage in the peristaltic pump head.
Save your process data directly on the BIOSTAT® A; then easily transfer this data to your PC or laptop spreadsheet application for convenient analysis.
Select the type and size of your culture vessel on the BIOSTAT® A menu, and all settings including PID parameters will be automatically adjusted.
The Advanced package version of the BIOSTAT® A with fedbatch control lets you achieve higher cell densities than with standard batch control. Easily implement substrate profiles in the menu to control an external variable-speed pump.
The BIOSTAT® A is available with single-wall glass vessels in a choice of working volumes of 1, 2 or 5 liters maximum. Whether you select our reusable UniVessel® Glass version or our disposable UniVessel® SU unit with a maximum 2-liter working volume, you can use the same system controller.
Both the UniVessel® Glass and the UniVessel® SU feature the classic stirred-tank design to give you comparable results. The advantage: The same motor drives the stirrer of both vessels so you can easily change over from reusable to single-use or vice versa.
Perform screening studies efficiently with multi-parallel cultivation. Screen your process variables and define the conditions for optimal cell growth and enhanced protein expression.
Download your trial data from the BIOSTAT® A to your notebook, tablet or smartphone. For fast and accurate analysis of your data, use our Chemometrics Toolbox installed on your notebook or PC.
The new aeration system of the BIOSTAT® A provides continuous automatic flow control over the full range of each gas used. As a result, BIOSTAT® A does not require any manual adjustment of flow meters and therefore eliminates problems with pulsed aeration. Setting up the bioreactor for use is straightforward: Just connect the aeration tubing, configure the aeration profile, enter the DO setpoint – that’s it! For cell culture applications, interfaces for four gases (air, O2, CO2 and N2) are available for DO and pH control. The microbial version features two gas lines (air and O2) for DO control.
Allows fermentation in any laboratory and minimizes water usage. You won’t need to worry about finding a suitable cooling water source for your bioreactor.
Thanks to the intuitive user interface, operating the BIOSTAT® A is ideal for beginners, reduces operating errors and speeds up training.
BIOSTAT® A is equipped with digital pH and DO probes. These help you immediately recognize whether you can use a probe for the next cultivation batch.
Our Chemometrics Toolbox assists you in efficiently optimizing key process parameters, such as titer or cell density, so you will obtain meaningful results faster from your experiments.
Thanks to its intuitive user guidance, this leading DoE software is the ideal tool for beginners in experimental design planning and performing trial runs, as well as analyzing and optimizing media and parameters for cultivation.
By performing only a few experiments, you can quickly and easily determine the relationship between process parameters and the relevant target figures, such as titer and product quality.
With BioPAT® SIMCA, you can quickly and easily compare the historical data of different cultivation batches to identify trends, correlations and dependencies.
The graphical user interface enables you to select the software functions intuitively. In addition, the Analysis Advisor guides you through the whole analysis process and generates easy-to-interpret graphs.
attach_fileCHO cell–based production of a secreted model protein using the novel BIOSTAT® A
attach_fileHigh cell density Escherichia coli cultivation in a BIOSTAT® A
attach_file采用 BIOSTAT® A, 通过 产丙酸丙酸杆菌 来生产丙酸。