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ambr® 250 modular


ambr® 250 modular is an innovative high performance benchtop bioreactor system for parallel fermentation or cell culture. Central to the system is a new 100-250 mL single-use vessel design, fully integrated with liquid reservoirs and...




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ambr® 250 modular


Mini bioreactor, 100-250 mLl


ambr® 250 modular is an innovative high performance benchtop bioreactor system for parallel fermentation or cell culture. Central to the system is a new 100-250 mL single-use vessel design, fully integrated with liquid reservoirs and syringe pumps.

  • Allows users to set up experiments quickly and easily, enabling them to focus more on the science
  • Experiments can be turned around rapidly, reducing the time required to complete an experimental campaign
  • Single-use, fully integrated vessel design eliminates the need for sterilization and reduces the risk of human error



Features


ambr® 250 modular combines bioreactor stations, a control module and software to offer an innovative high performance bioreactor system.

  • Control module manages individual vessel requirements including pH, temperature, DO and impeller speed for up to 8 bioreactors
  • Each bioreactor has an option of a fully dedicated off-gas analyser measuring both CO2 and O2 and generating CER and OUR data points
  • 3 step “easy connect” vessel installation for all gas, liquid and sensor connections
  • Touch screen user interface enables easy control and supervision of multiple bioreactors
  • Modular, expandable design offers parallel control of 2, 4, 6 or 8 bioreactor experiments to meet the growing needs of your lab

Vessels


ambr® 250 modular vessel is a new concept in bioreactors. The vessel is fully integrated with liquid reservoirs and proprietary syringe pumps; and the unit is single use.

This innovative design simplifies experimental set-up, significantly reduces manual handling and eliminates the need for vessel sterilization.

  • Fully disposable, single-use 100-250 mL bioreactors
  • Choice of mammalian or microbial vessels with pitch blade or Rushton impeller
  • 5 integrated liquid reservoirs (2 x 125 mL; 3 x 50 mL) with syringe pumps and liquid lines
  • Spot based DO sensor and disposable pH electrode
  • Integrated gas and liquid inlet filters
  • Sparge or headspace gassing options

Software


ambr® 250 modular is supplied with the same easy-to-use software as the established ambr® 250 high throughput system.

For ease of use and multi-tasking, the software has been designed as 4 separate applications:

  • Process definition: Simple “drag and drop” process steps for quick and easy definition of experiments
  • Runtime: Monitoring and adjustment of all process parameters in real time, for each individual bioreactor
  • Results viewer: Comparison of plots from experiments run at different times - allows parameters from multiple experiments to be plotted together on the same graph
  • Experiment viewer: Historical application enables users to fully analyse experiments looking at audit trails, all variables and completed recipes

All applications enable export and import of data to/from different sources.


Applications


ambr® 250 modular is configurable for both microbial fermentation and mammalian cell culture and can be used to model a wide range of processes in a variety of applications:

  • Biopharma R&D and process development
  • Industrial biotech R&D and process development
  • Process robustness experimentation in support of QbD studies
  • Vaccine process development

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ambr® 250 modular

ambr® 250 modular is an innovative high performance benchtop bioreactor system for parallel fermentation or cell culture. Central to the system is a new 100-250 mL single-use vessel design, fully integrated with liquid reservoirs and...