ambr<sup>®</sup> 15  |產品專區<br/>Products & Services  |生物製程解決方案<br/>Bioprocess Solutions    |生物反應器∣醱酵槽<br/>Bioreactors∣Fermentors   |細胞株開發<br/>Cell Line Development

ambr® 15


ambr® 15 Speeds up Cell Line Selection under True Bioreactor Conditions. Run up to 48 stirred vessels in parallel and screen for the best producing cell line and media combination with ......




Micro bioreactor, 10-15mL

ambr®15 cell culture is an automated microscale bioreactor system that replicates classical laboratory-scale bioreactors. It is widely used by major Pharma and biologics companies, academic and research institutes as a reliable microscale model for a range of upstream processes.

  • Improves early clone selection decisions by providing a predictive bioreactor model with pH and DO control
  • Increases lab productivity by managing multiple cell line development experiments (24 or 48) in parallel.
  • Reduces the cost per experiment by saving substantial amounts on facility space, capital, labour, media and consumables.
  • Helps create better cell lines faster by automating vessel set-up, feeding, base addition and sampling.
  • Simplifies adoption of quality by design (QbD) principles enabling large multifactorial experimental designs (DoE) in real time.
 

Features

  • Combines single-use micro bioreactor vessels, an automated workstation and user-friendly software.
  • Two versions available – offering parallel control of 24 or 48 bioreactor experiments using just one operator.
  • Closed loop control of pH and DO with independent control of O2 and CO2 for each vessel
  • Automated liquid handling for reactor set-up, feeds, base addition and sampling
  • Software enables easy experiment construction.  It controls and monitors all experiments and records data and events with a full audit trail.
  • Easy installation into laminar flow hood allowing aseptic operation
  • Optional integration with Beckman Coulter Vi-CELL® or Cedex HiRes cell viability analysers.

Vessels

  • Single-use micro bioreactors designed for use with the ambr® 15 cell culture workstation
  • pH and DO sensors  for continuous monitoring and control
  • Integral impeller for rapid, efficient mixing
  • Sparge tube delivers gas to the impeller mixing zone*
  • 10-15mL culture volume with sample port to allow addition of reagents and feeds or removal of samples

*Vessels are also available with no sparge tube for use where antifoam addition must be avoided.

Applications

ambr® 15 cell culture can be used as a microscale model to unlock bottlenecks in a range of development applications such as:

  • cell line selection
  • media development
  • media feed strategies
  • process optimisation
  • QbD and DoE studies

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ambr® 15

ambr® 15 Speeds up Cell Line Selection under True Bioreactor Conditions. Run up to 48 stirred vessels in parallel and screen for the best producing cell line and media combination with ......